Scientific Hand Charts Collection:
Cri-du-Chat syndrome!
4 Hand Charts for Cri-du-Chat syndrome!
Cri-du-chat syndrome (= cat cry syndrome or Lejeune's syndrome) also known as chromosome 5p- syndrome, is a rare genetic disorder due to a missing part of chromosome 5. Its name is a French term (call of the cat) referring to the characteristic cat-like cry of affected children, often featured with developmental & behavioral problems.
Prevalence: close to 1 in 30,000 live births have cri-du-chat syndrome.
Two hand charts are available for cri-du-chat syndrome describing the significance of various typical dermatoglyphic features often combined with a simian line (= single transverse flexion crease) - see pictures below.
NOTICE: Individual hand features described below should not get associated in isolation with any theme; only combinations involving multiple hand levels have potential for diagnostic purposes.
Hautleistenfibel (1981), p.79;
authors: A. Rodewald & H. Zankl
Dermatoglyphics in Medical Disorders (1976), p.186;
authors: B. Schaumann & M. Alter
Handbook of Clinical Dermatoglyphs (1971), p.37;
authors: M.S. Elbualy & J.D. Schindeler
Other significant hand signs (not reported inside the hand charts):
Short fingers also represents a common finding in cri-du-chat syndrome.
Additionally, according Wikipedia there is also a considerable list of hand signs which are reported to represent less frequently encountered findings - including: clinodactyly of the 5th fingers, syndactyly of the second and third fingers, oligosyndactyly, and hyperextensible joints.
Slightly short hand bones is also reported, involving especially the palm (source: K. Fenger & E Niebuhr, 1978): "Various measurements were performed on the hand radiographs of 32 Danish cri-du-chat probands. ... The hands were smaller than in normal persons of the same sex and age. In most of the probands, the 3rd, 4th, and 5th metacarpals were disproportionately short, and the 2nd, 3rd, 4th, and 5th proximal phalanges were disproportionately long. Only 1 case had a positive metacarpal sign."
All significant hand signs listed above for cri-du-chat syndrome together cover five out of the nine perspectives of the hand as defined according Multi-Perspective Hand Reading (including hand level 2, 4, 5, 8 & 9).
A summary of the most significant hand sign combinations in cri-du-chat syndrome is described here:
Decoding the language of the hand:
hand sign combinations in cri-du-chat syndrome!
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