Hand chart for the Big Five personality dimension Conscientiousness (2016) Hand chart for the Big Five personality dimension Extraversion (2016) Hand chart for the Big Five personality dimension Neuroticism (2016) Hand chart for hypercalcemia (1971) Hand chart for arthrogryposis (1981) Hand chart for cri-du-chat syndrome - Hautleistenfibel (1981) Hand chart for Down syndrome (2011) Hand chart for Edwards syndrome (1981) Hand chart for fragile-X syndrome (2014) Hand chart for Holt-Oram syndrome (1981) Hand chart for Kabuki syndrome (A. Chudley) Hand chart for Klinefelter syndrome (A. Rodewald & H. Zankl, 1981) Hand chart for Cornelia de Lange syndrome (A. Rodewald & H. Zankl, 1981) Hand chart for Patau syndrome (1981) Hand chart for Prader-Willi syndrome (1971) Hand chart for rubella syndrome (1971) Hand chart for Smith-Lemli-Opitz syndrome (1971) Hand chart for Turner syndrome - Hautleistenfibel (1981) Hand chart for Williams syndrome (R. Rodewald, 1994) Hand chart for Wolf-Hirschhorn syndrome (B. Schaumann & M. Alter, 1976) Hand chart for XXYY syndrome (1971) Hand chart for XYY syndrome (1971) Hand chart for 18p- syndrome, a.ka. de Grouchy syndrome 1 (1981)

- Some of the available hand charts are displayed above - you can use the displayed pictures above for browsing -


Publication: november 14, 2015

Hand Charts for Fragile-X syndrome!

Fragile-X (Xq27.3), a.k.a. Martin-Bell syndrome, is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females.

Prevalence: fragile X affects 1 in 4,000 males and 1 in 6,000 females of all races and ethnic groups; about 1 in 259 women carry fragile X and could pass it to their children.

Quite a few detailed hand charts are available for fragile-X syndrome; most charts describe the significance of various typical features inside especially the dermatoglyphics, which manifest often combined with a simian line (= single transverse flexion crease) or Sydney line.

(The first hand chart below also illustrates the significance of various proportions of the hand size in fragile-X syndrome)


NOTICE: Individual hand features described below should not get associated in isolation with any theme; only combinations involving multiple hand levels have potential for diagnostic purposes.

Hand chart for fragile-X syndrome (2013).
Hand chart source:
Fragile-X syndrome & the Hand: 36 Hand Signs! (2013);
author: M. van Mensvoort


Hand chart for fragile-X syndrome (1986).
Hand chart source:
Dermatoglyphic peculiarities in families with X-linked mental retardation and fragile site Xq27: a collaborative study (1986), p.8; authors: A. Rodewald et al.


Hand chart for fragile-X syndrome (1985).
Hand chart source:
Dermatoglyphische Befunde bei Patienten mit fragilen X-Chromosom im Rahmen ihren klinischen Bildes (1985), p.37; author: M. Muller
(dissertation study)




Other significant hand signs (not reported inside the hand charts):

Inside the first- and most detailed hand chart for fragile-X syndrome 28 hand signs are being reported; however the article where this hand chart is presented actually already describes 36+ hand signs in fragile-X syndrome, involving 8 out 9 levels of the hand.


All significant hand signs listed above for fragile-X syndrome together cover eight out of the nine perspectives of the hand as defined according Multi-Perspective Hand Reading (including hand level 1, 2, 3, 4, 5, 6, 8 & 9).

A summary of the most significant hand sign combinations in fragile-X syndrome is described here:

Decoding the language of the hand:
hand sign combinations in fragile-X syndrome!



Two detailed case studies for the hand in fragile-X syndrome
are present below:

Fragile-X syndrome & the hand: case study 1.
Adult hand involving fragile-X syndrome & the hand: case study 1.


Fragile-X syndrome & the hand: case study 2.
Adult hand involving fragile-X syndrome & the hand: case study 2.




Hand charts are available for many other diagnostic issues;
start browsing HERE


Martijn van Mensvoort - Hand Research

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