Hand chart for the Big Five personality dimension Conscientiousness (2016) Hand chart for the Big Five personality dimension Extraversion (2016) Hand chart for the Big Five personality dimension Neuroticism (2016) Hand chart for hypercalcemia (1971) Hand chart for arthrogryposis (1981) Hand chart for cri-du-chat syndrome - Hautleistenfibel (1981) Hand chart for Down syndrome (2011) Hand chart for Edwards syndrome (1981) Hand chart for fragile-X syndrome (2014) Hand chart for Holt-Oram syndrome (1981) Hand chart for Kabuki syndrome (A. Chudley) Hand chart for Klinefelter syndrome (A. Rodewald & H. Zankl, 1981) Hand chart for Cornelia de Lange syndrome (A. Rodewald & H. Zankl, 1981) Hand chart for Patau syndrome (1981) Hand chart for Prader-Willi syndrome (1971) Hand chart for rubella syndrome (1971) Hand chart for Smith-Lemli-Opitz syndrome (1971) Hand chart for Turner syndrome - Hautleistenfibel (1981) Hand chart for Williams syndrome (R. Rodewald, 1994) Hand chart for Wolf-Hirschhorn syndrome (B. Schaumann & M. Alter, 1976) Hand chart for XXYY syndrome (1971) Hand chart for XYY syndrome (1971) Hand chart for 18p- syndrome, a.ka. de Grouchy syndrome 1 (1981)

- Some of the available hand charts are displayed above - you can use the displayed pictures above for browsing -


Publication: december 19, 2015

Hand Charts for XXYY syndrome!

48, XXYY syndrome is a sex chromosome anomaly in which males have an extra X and Y chromosome. The syndrome was originally considered a variation of Klinefelter syndrome, and XXYY is still considered a variation of Klinefelter syndrome by some definitions - because the pathophysiology of the testicular dysfunction has not been shown to differ from 47, XXY, and the most current research does not suggest that there should be any differences in the evaluation and treatment of testosterone deficiency in 48, XXYY compared to 47, XXY. However, for the psychological and behavioral symptoms of XXYY syndrome, more extensive evaluations, interventions, and supports are usually needed compared to 47, XXY due to more complex neurodevelopmental involvement.

Prevalence: close to 1 in 30,000 male births have XXYY syndrome.

One superficial hand chart is available for XXYY syndrome describing only 3 characteristics in the dermatoglyphics, involving: 1) increased arches (occurs in 17%), 2) Mean ridge count reduced to 90-106, 3) atd angle increased: axial triradius associated with either arch-carpal (A) or loop-radial (B) hypothenar pattern - see picture below.


NOTICE: Individual hand features described below should not get associated in isolation with any theme; only combinations involving multiple hand levels have potential for diagnostic purposes.

Hand chart for XXYY syndrome - Handbook of Clinical Dermatoglyphs (1971).
Hand chart source:
Handbook of Clinical Dermatoglyphs (1971), p.44;
authors: M.S. Elbualy & J.D. Schindeler




Other significant hand signs (not reported inside the hand chart):

Because of hand tremors, XXYY males may have significant difficulties with writing; the development of a tremor typically starts in adolescence and worsens with age (source: Genetics Home Reference).

Parents of XXYY children recognized nail biting as part of the behavioral phenotype of XXYY (source: M. Tartaglia et al., 2008).

In one study a high prevalence of the simian crease has been reported: 21.4% (source: D.S. Borgaonkar et al., 1970)

Clinodactyly (curved-in pinky fingers) is recognized to belong to the most common physical features in prepubertal XXYY children - see picture below (source: M. Tartaglia et al., 2008).

5th finger clinodactyly in XXYY syndrome.
5th finger clinodactyly in XXYY syndrome.


All significant hand signs listed above for XXYY syndrome together cover five out of the nine perspectives of the hand as defined according Multi-Perspective Hand Reading (including hand level 1, 2, 5, 8 & 9).

A summary of the most significant hand sign combinations in XXYY syndrome is described here:

Decoding the language of the hand:
hand sign combinations in XXYY syndrome!





Hand charts are available for many other diagnostic issues;
start browsing HERE


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