Martijn van Mensvoort - © Hand Research

 



HAND RESEARCH

HAND SIGNS & DIAGNOSTICS:

• The hand in SCHIZOPHRENIA!
• The hand in DIABETES MELLITUS!
• The hand in RHEUMATOID ARTHRITIS!
• The hand in PSORIASIS!

• The hand in DOWN SYNDROME!
_- Down syndrome case study 1
_- Down syndrome case study 2

• The hand in FRAGILE-X SYNDROME!
_- Fragile-X syndrome case study 1
_- Fragile-X syndrome case study 2
_(In people with autism 2% to 6% have Fragile-X syndrome!)



Hand signs & anthropometry data in Schizophrenia:




Phantom picture for the hand in Schizophrenia.

SIMIAN LINE INDEX:

INTRO: About the Simian Line (a.k.a. 'simian crease')

• HOW TO RECOGNIZE a 'complete' Simian Line?
• WHY PALM CREASE NAMED the Simian Line?
• BRIEF HISTORY of the Simian Line
• ETHNIC POPULATIONS & the Simian Line
• MEDICAL PROBLEMS & the Simian Line
• PSYCHOLOGY & the Simian Line
• PROJECTS related to the Simian Line
• SYNONYMS for the Simian Line
• FAMOUS Simian Line holders

Video - understanding Schizophrenia:






MORE HAND DIAGNOSTICS:

• The hand lines (palmar creases)
• The Sydney line
• Fingerprints (+ dermatoglyphics)
• The Hypothenar whorl
• The 5th finger (pinky)
• The fingernail tutor

More news - hands on health care!

EARLY HAND DIAGNOSTICS:
& HANDS ON HEALTH CARE!!








THE TOP 10 HAND SIGNS
IN SCHIZOPHRENIA:


(Ranked by 'Log Odds Ratio' = LOR)

I - Excessive secundary creases
[Schizophrenia hand sign 4-6: LOR = +3.40]

II - Pinky: imobility (ankylosis)
[Schizophrenia hand sign 7-1: LOR = +3.02]

III - Lack of expression / rigid expression
[Schizophrenia hand sign 1-2: LOR = +2.77]

IV - Visible nail fold plexus
[Schizophrenia hand sign 6-1: LOR = +2.74]

V - Sydney line
[Schizophrenia hand sign 4-2: LOR = +2.45]

VI - Nails: small & underdeveloped (rudimentary)
[Schizophrenia hand sign 2-1: LOR = +2.43]

VII - Chaotic arrangement of secundary creases
[Schizophrenia hand sign 4-7: LOR = +2.32]

VIII - Simian crease
[Schizophrenia hand sign 4-1: LOR = +2.27]

IX - Atypical handedness
[Schizophrenia hand sign 7-3: LOR = +1.80]

X - Nails: excessively curved outwards (hyperconcex nails)
[Schizophrenia hand sign 2-2: LOR = +1.74]


This TOP 10 shows that the fingertips play a key-role in recognizing Schizophrenia (see hand signs I, IV, VI & X), involving the accessory creases on the fingertips, nail fold plexus visibility (concerning blood stream papillaries) & nail shape.


NOTICE: Log Odds Ratios are calculated from the prevalence (%) among Schizophrenia patients & controls; more details are presented in the right column at the bottom of this page.

 


- 37 Hand Signs in Schizophrenia -

Schizophrenia is a rather complex psychiatric disorder. The result of many studies indicate that there is no single hand sign that can be described as 'typical' for schizophrenia [log odds ratio statistics are always below 3.5].

Nevertheless, the result of many studies do show that various (combinations of) hand signs signal the presence of unusual biological mechanisms that are featured with Schizophrenia. Rather remarkable: quite some of these hand signs relate to the tips of the fingers!

• 37 Hand signs significant for Schizophrenia
• TOP 10 - Schizophrenia: the ten most significant hand signs!
• How to make a hand-diagnosis for Schizophrenia: 4 requirements!







Multi-perspective palm reading.

How to make a Palm Reading Assessment
for SCHIZOPHRENIA?

The following guidelines should be applied solely to hands of persons who exhibit psychotic symptoms - in thought, emotion or behavior - that are associated with pschizophrenia

Key-elements of the hand in schizophrenia in a nutshell: combination of inborn hand markers & 'dynamic' hand markers, combined with special attention for the fingertips.

Schizophrenia.
Phantom picture for Schizophrenia.

[Phantom picture for Schizophrenia will become available soon]


An advanced hand diagnosis for Schizophrenia requires a person to have multiple significant hand markers that follow the MAJOR REQUIREMENT + the 4 additional requirements as described below:

MAJOR REQUIREMENT: The person requires to have significant hand markers for Schizophrenia in at least 4 dimensions of the hand

- ADDITIONAL REQUIREMENT A: The person requires to have three 'dynamic hand markers' (= not inborn) that relate to one or both of the following two sub-requirements:
REQUIREMENT A-1 - a lack of expression through: the back of the hand, thumb, nails, dermatoglyphics or mobility problems (see hand perspectives: 1 - 2 - 3 - 5 - 7);
REQUIREMENT A-2 - too much expression through: skin colour, secundary creases (see hand perspective: 2 - 4 - 6).

- ADDITIONAL REQUIREMENT B: The person requires to have at least one hand marker that relates to the CREASES (= hand perspective 4).

- ADDITIONAL REQUIREMENT C: The person requires to have at least three hand markers that relate to the DERMATOGLYPHICS (= hand perspective 5).

- ADDITIONAL REQUIREMENT D: The person requires to have at least two hand markers in the palm + at least two hand markers in the fingers.




IMPORTANT: Even when all above REQUIREMENTS are fullfilled, then one can still speak of a 'speculative' hand diagnosis for Schizophrenia!

Some of the 37 significant hand markers for Schizophrenia that are listed below became known in medical science as a 'physical minor anomaly' (such as the simian crease & the Sydney line).
But in general all these individual hand markers can usually be described as harmless body characteristics. And even when 'constellations' of two or more of these hand markers are observed in one perspective of the hand, these hand markers should not be recognized as suspicious - UNLESS each of both hands display such constellations in 2 or more perspectives of the hand.







- List of 37 hand markers for Schizophrenia -


• Hand perspective 1 - HAND SHAPE:
- 1-1: Conic handshape: long & narrow;
- 1-2: Back of hand: lack of expression / rigid expression;
- 1-3: Relatively small mount of venus (thenar hypotrophy).

• Hand perspective 2 - FINGERNAILS:
- 2-1: Nails: small & underdeveloped (rudimentary);
- 2-2: Nails: excessively curved outwards (hyperconcex fingernails).

• Hand perspective 3 - FINGER MORPHOLOGY:
- 3-1: Spatulate fingertips;
- 3-2: Small distal phalanages (microphalangia);
- 3-3: Thumbs: small + short;
- 3-4: Thumb: lack of expression / rigid expression;
- 3-5: Thumb: extraordinary long (above 2nd knuckl);
- 3-6: Index finger: extraordinary long - equal or longer than middle finger;
- 3-7: 'Female' finger ratio (2D:4D digit ratio > 1);
- 3-8: Pinky: curved inwards (clinodactyly);
- 3-9: Pinky: extraordinary long;
- 3-10: Pinky: extraordinary short.

• Hand perspective 4 - MAJOR LINES:
- 4-1: Simian crease;
- 4-2: Sydney line;
- 4-3: Broken head line (broken proximal transverse crease)
- 4-4: Broken heart line (broken distal transverse crease)
- 4-5: Indistinct / fragmented primary creases;
- 4-6: MINOR LINES: Excessive secundary creases;
- 4-7: MINOR LINES: Chaotic arrangement of secondary creases.

• Hand perspective 5 - DERMATOGLYPHICS:
- 5-1: Fingers: fingerprint type asymmetries (at least 3 out of 5 fingers);
- 5-2: Fingers: extralimital triradii;
- 5-3: Palm: ridge dissociation ('string of pearl type').
- 5-4: Palm: pattern on the mount of venus / mouse thumb (thenar);
- 5-5: Palm: pattern on mount of mars;
- 5-6: Palm: Whorl or multiple loops on hypothenar;
- 5-7: Palm: multiple triradii on the hypothenar;
- 5-8: Palm: missing c triradius / merging of triradius b and triradius c;
- 5-9: Palm: abortive c line;
- 5-10: Palm: large ab ridge count fluctuating asymmetry: [LABRC-RABRC] > 5.

• Hand perspective 6 - SKIN QUALITY:
- 6-1: Nail fold: visible nail fold plexus (subpapillary plexus);
- 6-2: Red/blue coloured + cold.

• Hand perspective 7 - MOTORICS:
- 7-1: Pinky: imobility (ankylosis);
- 7-2: Impaired hand movement;
- 7-3: Atypical handedness.


NOTICE: About 0.5% of the world population suffers on symptoms that relate to Schizophrenia. The 4 schizophrenia sub-types are not treated individually, because in the near future (likely in 2013) those are probably no longer included in the DSM V classification system for mental disorders.



Additionally, there are two case studies available:

Schizophrenia case 1:

The hand in schizofrenia: case 1.
Schizophrenia case 2:

The hand in schizofrenia: case 2.

(A more detailed analysis for these cases will be available later)


- MORE MULTI-PERSPECTIVE PALM READING -

The hand in DIABETES MELLITUS
The hand in RHEUMATOID ARTHRITIS
The hand in PSORIASIS
The hand in FRAGILE-X SYNDROME

More about Schizophrenia + related studies of the hand



SCHIZOPHRENIA: HOW TO MAKE A HAND DIAGNOSIS VIA 'MULTI-PERSPECTIVE PALM READING'!

THE FAMOUS 'SIMIAN LINE' (SINGLE PALMAR CREASE) IS ONLY A MINOR KEY-ELEMENT FOR THE HAND IN SCHIZOPHRENIA


Hand Diagnostics:
the Simian Line & 37 markers in Schizophrenia!

Various studies around the world have proven that the simian line is more often seen among schizophrenics than in the general population (about 3% of the healthy population has a simian line in at least one hand).

This implicates that the simian line is much more important in the genetic syndromes (e.g. Down syndrome & Fragile-X syndrome) than in Schizophrenia - but still, combined with other relevant hand markers the simian line can play a role in a (speculative) hand diagnosis for Schizophrenia, but only when an individual suffers on symptoms that can be associated with schizophrenia.

This raises the question: 'how can the simian line serve as a diagnostic marker specific for Schizophrenia?'

'Phantom picture' of the hand in Schizophrenia.

Phantom picture for Schizophrenia: including the simian line.

NOTICE: Later the author will present a more comprehensive 'phantom picture' for the most typical hand-characteristics in Schizophrenia.



HAND SHAPE & SCHIZOPHRENIA:

• 1-1 - Conic hand type: long & narrow
Prevalence: Schizophrenic patients: 48-96 %; controls - 34-62 % 5,7

LOG ODDS RATIO: +1.02

• 1-2 - Back of hand: lack of expression / rigid expression
Prevalence: Schizophrenic patients: 80 %; controls - 20 % 7

LOG ODDS RATIO: +2.77

• 1-3 - Relatively small mount of venus (thenar hypotrophy)
Prevalence: Schizophrenic patients: ? %; controls - ? % 6

LOG ODDS RATIO: ? (unknown)



FINGERNAILS & SCHIZOPHRENIA:

• 2-1 - Nails: small & underdeveloped (rudimentary)
Prevalence: Schizophrenic patients: 18.8 %; controls - 2.0 % 5

LOG ODDS RATIO: +2.43

• 2-2 - Nails: excessively curved outwards (hyperconcex fingernails)
Prevalence: Schizophrenic patients: 15 %; controls - 3 % 17

LOG ODDS RATIO: +1.74



FINGER MORPHOLOGY & SCHIZOPHRENIA:

• 3-1 - Fingers: spatulate fingertips
Prevalence: Schizophrenic patients - 42.4 %; controls - 21.7 % 5

LOG ODDS RATIO: +0.98

• 3-2 - Fingers: small distal phalanages (microphalangia)
Prevalence: Schizophrenic patients - ? %; controls - ? % 6

LOG ODDS RATIO: ? (unknown)

• 3-3 - Thumb: lack of expression / rigid expression
Prevalence: Schizophrenic patients: 80 %; controls - 20 % 7

LOG ODDS RATIO: +2.77

• 3-4 - Thumbs: small + short
Prevalence: Schizophrenic patients: 15.1-20.0 %; controls - 0-10.0 % 5-7

LOG ODDS RATIO: +1.40 (average)

• 3-5 - Thumb: extraordinary long (above 2nd knuckl)
Prevalence: Schizophrenic patients: 2.6-4.5 %; controls - 0-2.2 % 4,5

LOG ODDS RATIO: +1.19 (average)

• 3-6 - Index finger: extraordinary long - equal or longer than middle finger
Prevalence: Schizophrenic patients: ? %; controls - ? % 4

LOG ODDS RATIO: ? (unknown)

• 3-7 - 'Female' finger ratio (2D:4D digit ratio > 1)
Prevalence: Schizophrenic patients: 33.1 %; controls - 10.8 % 5,18-20

LOG ODDS RATIO: +1.41

• 3-8 - Pinky: curved inward (clinodactyly)
Prevalence: Schizophrenic patients: 68 %; controls - 41 % 17

LOG ODDS RATIO: +1.12

• 3-9 - Pinky: extraordinary long
Prevalence: Schizophrenic patients: 44.5 %; controls - 12.5 % 5

LOG ODDS RATIO: +1.72

• 3-10 - Pinky: extraordinary short
Prevalence: Schizophrenic patients: 13.4 %; controls - 5.0-10.0 % 5

LOG ODDS RATIO: +0.65 (average)



HAND LINES & SCHIZOPHRENIA:

• 4-1 - Simian crease (SRBC)
Prevalence: Schizophrenic patients: 10.0-53.0 %; controls - 1.2-7.9 % 1-5

LOG ODDS RATIO: +2.27 (average)

• 4-2 - Sydney line
Prevalence: Schizophrenic patients: 15.0 %; controls - 1.5 % 1-3

LOG ODDS RATIO: +2.45

• 4-3 - Broken head line (broken proximal transverse crease)
Prevalence: Schizophrenic patients - 26.9 %; controls - 19.0 % 5,6

LOG ODDS RATIO: +0.45

• 4-4 - Broken heart line (broken distal transverse crease)
Prevalence: Schizophrenic patients - ? %; controls - ? % 6

LOG ODDS RATIO: ? (unknown)

• 4-5 - Indistinct / fragmented (multiple) primary creases
Prevalence: Schizophrenic patients - 30.7 %; controls - 6.7 % 7

LOG ODDS RATIO: +1.82

• 4-6 - MINOR LINES: Excessive secundary creases
Prevalence: Schizophrenic patients - 15.0-40.0 %; controls - 0-2.5 % 7-9

LOG ODDS RATIO: +3.40 (average)

• 4-7 - MINOR LINES: Chaotic arrangement of secundary creases
Prevalence: Schizophrenic patients - 7.3-95.3 %; controls - 0-18.8 % 7

LOG ODDS RATIO: +2.32 (average)


DERMATOGLYPHICS & SCHIZOPHRENIA:

• 5-1 - Fingerprint type asymmetries, on at least 4 out of 5 fingers
Prevalence: Schizophrenic patients: ? %; controls - ? % 15,27-29

LOG ODDS RATIO: ? (unknown)

• 5-2 - Extralimital triradii
Prevalence: Schizophrenic patients: 6.6 %; controls - 1.5 % 10

LOG ODDS RATIO: +1.53

• 5-3 - Rige dissocations, multiple areas e.g. on distal hypothenar (string of pearl type)
Prevalence: Schizophrenic patients: 10.5-22.65 %; controls - 6.5-7.3 % 1,2,11

LOG ODDS RATIO: +0.99 (average)

• 5-4 - Pattern on the mount of venus / mouse thumb (thenar)
Prevalence: Schizophrenic patients: 19.8 %; controls - 8.3 % 1

LOG ODDS RATIO: +1.00

• 5-5 - Pattern on the mount of mars (interdigital area II)
Prevalence: Schizophrenic patients: 19.8 %; controls - 8.3 % 1

LOG ODDS RATIO: +1.00

• 5-6 - Whorl or multiple loops on hypothenar
Prevalence: Schizophrenic patients: 15.9 %; controls - 7.7 % 1,12,13

LOG ODDS RATIO: +0.82

• 5-7 - Multiple triradii on the mount of moon (multiple hypothenar triradii)
Prevalence: Schizophrenic patients: 15.9 %; controls - 7.7 % 1

LOG ODDS RATIO: +0.82

• 5-8 - Missing c triradius / merging of triradius c and triradius b
Prevalence: Schizophrenic patients - ? %; controls - ? % 6

LOG ODDS RATIO: ? (unknown)

• 5-9 - Abortive c line
Prevalence: Schizophrenic patients - 1.5 %; controls - 0.5 % 1

LOG ODDS RATIO: +1.11

• 5-10 - Large ab ridge count asymmetry: [LABRC - RABRC] > 5
Prevalence: Schizophrenic patients - ? %; controls - ? % 14-16

LOG ODDS RATIO: ? (unknown)



HAND MOTORICS IN SCHIZOPHRENIA:

• 6-1 - Visible nail fold plexus
Prevalence: Schizophrenic patients: 20-70 %; controls - 3-7 % 26

LOG ODDS RATIO: +2.74 (average)

• 6-2 - Red/blue coloured + cold
Prevalence: Schizophrenic patients: ? %; controls - ? % 5

LOG ODDS RATIO: ? (unknown)



HAND MOTORICS IN SCHIZOPHRENIA:

• 7-1 - Pinky: imobility (ankylosis)
Prevalence: Schizophrenic patients: 2.0 %; controls - 0 % 5

LOG ODDS RATIO: +3.02

• 7-2 - Impaired hand movement function, related to eye-hand movements
Prevalence: Schizophrenic patients: ? %; controls - ? % 21-23

LOG ODDS RATIO: ? (unknown)

• 7-3 - Atypical handedness
Prevalence: Schizophrenic patients: 20 %; controls - 3.8 % 24,25

LOG ODDS RATIO: +1.80


(More details will become available later; a few more guidelines are available at: Schizophrenia & Multi-Perspective Palm Reading)


SOURCES:

1)
Dermatoglyphics of Schizophrenics. A. Bagga, 1989

2) Congenital Dermatoglyphic Malformations and Psychosis: A Twin Study. A. Rosa, et al., 2000

3) Dermatoglyphics in female schizophrenia: A preliminary report. D. Stowens, et al., 1970

4) Significance of morphological features in schizophrenia of a Chinese population. C.J. Huang, et al., 2009

5) The Hand in Psychological Diagnosis. C. Wolff, 1951

6) Subtle signs of prenatal maldevelopment of the hand ectoderm in schizophrenia: a preliminary monozygotic twin study. H.S. Bracha, et al., 1991

7) Differences between Schizophrenics and Normal Controls Using Chirological (Hand) Testing. Y. Haft, et al., 1982

8) Further evidence for anomalies in the hand-prints of patients with schizophrenia: a study of secondary creases. M. Canon, et al., 1994

9) Ein Versuch, Handabdrόcke in die Diagnostik von Psychosen aus dem schizophrenen Formenkreis einzubeziehen (mit acht Abbildungen) B. Ismail, et al., 1998

10) Extralimital triradii as a putative marker of schizotypy. J.T. Chok & T.R. Kwapil, 2005

11) Further Evidence That Congenital Dermatoglyphic Abnormalities Are Associated With Psychosis: A Twin Study. A. Rosa, et al., 2002

12) 'Dermatoglyphics in hungarian schizophrenic patients' in : Trends in Dermatoglyphic Research. G. Gyenis, et al., 1990

13) A palmar dermatoglyphic study in schizophrenia. O.R. Chackravortty, et al., 2007

14) Prenatal growth markers in schizophrenia: a monozygotic co-twin control study. J.O. Davis & H.S. Bracha, 1996

15) Fluctuating Dermatoglyphic Asymmetry and the Genetics of Liability to Schizophrenia. T.A. Markow & K. Wandler, 1986

16) Dermatoglyphic study of positive and negative symptoms of schizophrenia. F. Pαez, et al., 2001

17) Minor Physical Anomalies in Schizophrenic Patients and Their Siblings. B. Ismail, et al., 1998

18) Increased ratio of 2nd to 4th digit (2D:4D) in schizophrenia. S.L. Collinson, et al., 2010

19) Digit length pattern in schizophrenia suggests disturbed prenatal hemispheric lateralization. M. Aratσ, et al., 2004

20) Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: Altered prenatal gonadal hormone levels as a risk factor. D.J. Walder, et al., 2006

21) Digitized analysis of abnormal hand–motor performance in schizophrenic patients. P. Tigges, et al., 1999

22) Predictive eye and hand movements are differentially affected by schizophrenia. U. Sailer, et al., 2007

23) Neuromotor Precursors of Schizophrenia. E.F. Walker, et al., 1994

24) Is There Atypical Handedness in Schizophrenia? M.F. Green, et al., 1988

25) Handedness in schizophrenia: a quantitative review of evidence. M. Dragovich & G. Hammond, 2005

26) Relationship between nailfold plexus visibility and clinical, neuropsychological, and brain structural measures in schizophrenia. C.E. Curtis et al., 1999

27) Determining the association between dermatoglyphics and schizophrenia by using fingerprint asymmetry measures. J.-F. Wang et al., 2008

28) Neurodevelopmental Interactions Conferring Risk for Schizophrenia: A Study of Dermatoglyphic Markers in Patients and Relatives. M.T. Avila, 2003

29) Dermatoglyphic evidence of fluctuating asymmetry in schizophrenia. C.S. Mellor, 1992

 


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