THE TOP 10 HAND SIGNS FOR
RECOGNIZING FRAGILE-X SYNDROME:
(Ranked by 'Log Odds Ratio' = LOR)
I - Sydney line [LOR > 37]
II - Ridge line A: ends btw. finger 5 & heart line [LOR > 31]
III - Triradius b: missing (or ridge line B is 'abortive') [LOR > 27]
IV - Fingerprints: radial loop on thumb [LOR > 26]
V - Ridge line C: 'abortive' [end close to triradius c] [LOR > 25]
VI - Simian crease [LOR > 21]
VII - Double-jointed thumbs [hypermobility] [LOR > 15]
VIII - Fingerprints: arch on ring finger [LOR > 9]
IX - Fingerprints: arch on pinky finger (in males only) [LOR > 8]
X - Palmar triradius d: missing [LOR > 8]
This TOP 10 shows that dermatoglyphics in the upper half of the hand (palmar zone below the fingers + fingerprints) play a key-role in recognizing Fragile-X syndrome (see hand signs II, III, IV, V, VIII, IX & X); 4 of these hand signs relate to the palmar zone below the fingers and 3 of these hand signs relate to the fingerprints.
NOTICE: Log Odds Ratios are calculated from the prevalence (%) among Fragile-X syndrome patients & controls; more details are presented in the right column at the bottom of this page.
- The Hand in Fragile-X Syndrome: case 2 -
FRAGILE-X SYNDROME (XQ27): HOW TO MAKE A HAND DIAGNOSIS VIA 'MULTI-PERSPECTIVE PALM READING'!
The hand in Fragile X syndrome:
CASE 2 (male, retarded IQ)
[A larger picture is available at the bottom of this page!]
• Hand perspective 1 - HAND SHAPE:
- High hand index: palm width vs. hand length (ratio > 47 %): YES;
- Short palm length vs. palm width (squarish shaped: ratio > 85 %): YES.
• Hand perspective 2 - FINGERNAILS:
- (No elements identified yet)
• Hand perspective 3 - FINGER MORPHOLOGY:
- Finger length is long compared to palm length (ratio > 85 %): NO;
- Finger length is short compared to palm width (ratio < 95 %): YES;
- Incurved pinky finger (clinodactyly): YES.
• Hand perspective 4 - MAJOR LINES:
- Simian crease: NO;
- Sydney line: NO;
- Abnormally long heart line (extended distal transverse crease): NO.
• Hand perspective 5 - DERMATOGLYPHICS:
- Fingerprints: radial loop on thumb: UNKNOWN;
- Fingerprints: radial loop on both index fingers: NO;
- Fingerprints: radial loop on middle finger: NO;
- Fingerprints: arch on pinky finger, but not on the index finger of the same hand: NO;
- Fingerprints: arch on ring finger, but not on the index finger of the same hand: NO;
- Fingerprints: arch on middle finger, but not on the index finger of the same hand: NO;
- Fingerprints: large whorl on middle finger + large whorl on other fingers: YES;
- Fingerprints: double loops on pinky finger: YES;
- Fingerprints: high, small loops on various fingers: NO;
- Palm: radial loop on mount of venus (thenar radial loop), combined with a radial loop on at least one finger: NO;
- Palm: in both hands ridge line A ends between pinky finger & heart line (ridge line A starts in triradius below index finger): YES;
- Palm: ridge line A ends between index finger & middle finger (ridge line A starts in triradius below index finger): YES;
- Palm: a-b ridge count summarized for both hands < 70 (ridge count between triradius below index finger & triradius below middle finger): YES;
- Palm: ridge line B ends between middle finger & ring finger in both hands (ridge line B starts in triradius below middle finger): NO;
- Palm: ridge line C ends between middle finger and index finger, or in the a triradius, or at radial side of the palm (ridge line C starts below ring finger): NO;
- Palm: ridge line C ends below ring finger (abbortive ridge line C): NO;
- Palm: ridge line D ends at radial side of the palm (ridge line D starts in triradius below pinky): NO;
- Palm: triradius below middle finger is missing: NO;
- Palm: triradius below ring finger is missing in the left hand, or in both hands: NO;
- Palm: triradius below pinky finger is missing: NO;
- Palm: 'empty hands' = absence of palmar loops/whorls: NO;
- Palm: large areas with broken skin ridges (ridge dissociation / dysplasia): NO.
• Hand perspective 6 - SKIN QUALITY:
- (No elements identified yet)
MAJOR REQUIREMENT: The person requires to have significant hand markers for Down syndrome in at least three dimensions of the hand: YES
ADDITIONAL REQUIREMENT A: The person requires to have four or more hand markers that relate to DERMATOGLYPHICS (= hand perspective 5):YES
ADDITIONAL REQUIREMENT B: The person requires to have at least one hand marker that relates to the HANDSHAPE (= hand perspective 1) or FINGER MORPHOLOGY (= hand perspective 3): YES
ADDITIONAL REQUIREMENT C: The person requires to have at least one hand marker in the palm + at least one hand marker in the fingers.: YES
CONCLUSION:
The hands of this person (who has Fragile-X syndrome) meet the MAJOR REQUIREMENT for Down syndrome plus the three ADDITIONAL REQUIREMENTS as described by Multi-Perspective Palm Reading.
Therefore the hand markers in this person confirm the diagnosis Down syndrome!
[More details about these hands are presented below]
The hands above are from a female person who has fragile X syndrome (including: autism + normal IQ).
An analysis reveals that this person has 2 out of the 11 most significant hand characteristics for fragile X syndrome (see characteristics: 25 & 26).
A complete analysis reveals that this person has 8 1/2 of the 28 typical hand characteristics [hand lines: 0 characteristics; hand dermatoglyphics: 5 characteristics; hand shape: 4 characteristics].
The details are presented below.
A - HAND LINES IN FRAGILE X SYNDROME (1-2):
• 1 - NO Simian crease
• 2 - NO Sydney line
B - HAND DERMATOGLYPHICS IN FRAGILE X SYNDROME (3-24):
• 3 - NO Fingerprints: radial loops on thumb
• 4 - NO Fingerprints: radial loop on index finger - both hands
• 5 - YES Fingerprints: ulnar loop missing on index finger - both hands
• 6 - NO Fingerprints: radial loop on middle finger
• 7 - NO Fingerprints: arch on middle finger (males only)
• 8 - YES Fingerprints: whorl on middle finger - both hands
• 9 - NO Fingerprints: arch on ring finger (males only)
• 10 - NO Fingerprints: arch on pinky (males only)
• 11 - YES Palmar ridge line A: ends between index finger & middle (or returns into the a triradius)
• 12 - YES Palmar ridge line A: ends between pinky finger & distal transverse crease - in both hands!
• 13 - YES A-b ridge count < 70
• 14 - NO Palmar triradius b: missing (or palmar ridge line B is 'abortive')
• 15 - NO Palmar ridge line B: ends between middle finger & ring finger (or returns into the b triradius) - in both hands!
• 16 - NO Palmar triradius c: missing in left hand (or both hands)
• 17 - NO Palmar ridge line C: 'abortive' (stops at short distance below triradius c)
• 18 - NO Palmar ridge line C: ends between pointer finger & middle finger (or: in/below a triradius)
• 19 - NO Palmar triradius d: missing
• 20 - NO Palmar ridge line d: ends below the a triradius (at the thumb side of the palm)
• 21 - YES Alignment of ridges over the distal palmar area: 'transverse'
• 22 - NO Thenar (mount of venus): radial loop
• 23 - NO Full palm: empty hands (absence of true patterns: loops/whorls)
• 24 - NO Dysplasia: palmar ridge dissociation (broken skin ridges)
C - HAND MORPHOLOGY IN FRAGILE X SYNDROME (25-28):
• 25 - UNKNOWN Fingers: hyperextensible finger joints
• 26 - UNKNOWN Thumb: 'double-jointed thumbs' (hypermobility)
• 27 - NO Fingers: relatively long to hand length, short to palm width
• 28 - YES Palm: relatively broad to palm length and finger length.
HAND SIGNS & DIAGNOSTICS:
